الحماض الاستقلابي في الحماض اللبني المشير إلى تسمم الميتفورمين

References

DOI: 10.1053/j.ajkd.2019.01.036

• Metformin-associated lactic acidosis is defined by arterial lactate above 5 mmol/L and pH below 7.35 during metformin treatment.
• In case of lactic acidosis suggestive of metformin poisoning, the experts suggest early initiation of renal replacement therapy when there is an organ dysfunction or in the absence of improvement in the first hours of therapeutic management (EXPERT OPINION).
• Renal replacement therapy is intended to correct water–electrolyte and acid–base disturbances and to ensure metformin clearance.