علاج الميلانوما الجلدية الموضعية — الورم الأولي دون نقائل إلى العقد الليمفاوية الإقليمية أو نقائل بعيدة

Proposed algorithm for the management of patients with pT1b-pT4b cN0 cM0 melanoma.

Full depth, wide local excision (WLE) of primary tumours (with safety margins of 0.5 cm for in situ melanomas, 1 cm for tumours with a thickness of 2 mm and 2 cm for tumours thicker than 2 mm) is recommended.

Modifications, with reduced safety margins, or micrographic surgery, are acceptable for preservation of function in acral and facial melanomas, including lentigo maligna melanoma.

Full depth, WLE of primary tumours with safety margins of 0.5 cm for in situ melanomas, 1 cm for tumours with a thickness 2 mm and 2 cm for tumours >2 mm is recommended [III, B].