علاج الميلانوما مع النقائل العبورية أو الساتلية

References

1. Patients with resectable ITMs should undergo complete excision with clear margins [IV, B].
2. Patients with unresectable satellite or ITMs may be treated with systemic therapy with anti-PD-1 based immunotherapy or BRAFieMEKi, according to BRAF mutation status [I, A].
3. Local therapy with T-VEC, [I, B; ESMO-MCBS v1.1 score: 3], isolated limb infusion or isolated limb perfusion [IV, C], RT [IV, C], electrochemotherapy [IV, C] or limited palliative excision [IV, C] can also be considered (no impact on OS).