علاج ورم الغمد العصبي المحيطي الخبيث الموضعي دون نقائل بعيدة

References

DOI: 10.3390/cancers16193266

• For localized MPNST, complete surgical excision with clear margins is a pivotal element of potentially curative management.
• Pre- or post-operative radiotherapy has a significant role in localized disease by reducing the risk of local relapse in MPNSTs of the extremities, trunk or head and neck, especially when there are close margins or R1 on the surgical specimen.
• The usual dose of RT delivered was often in excess of 50 Gray (Gy) via different types of external RT.
• The literature generally recommends that RT is most useful in patients with large (>5 cm), high-grade tumours and/or those with R1 resections.