ضعف الانتصاب مع النترات العضوية أو النيكورانديل: عندما لم تنجح علاجات الخط الأول

References

• An absolute contraindication to PDE5Is is the concomitant use of any form of organic nitrate or nitric oxide donors, including recreational use of amyl nitrite or nitrate (poppers).
• Concurrent use of nicorandil and PDE5Is is contraindicated due to the potential of the nitric oxide donating properties of nicorandil to increase cGMP levels.
• Implant a penile prosthesis if other treatments fail or depending upon patient preference.
• The surgical implantation of a penile prosthesis may be considered in patients who i) are not suitable for different pharmacotherapies or prefer a definitive therapy; and, ii) do not respond to other treatment modalities.
• The two currently available classes of penile implants include inflatable (two- and three-piece) and semi-rigid devices (malleable, mechanical and soft flexible).
• Efficacy is defined as an erection, with rigidity, sufficient for satisfactory intercourse.