علاج ساركويدوز العقد اللمفاوية والطحال عند عدم كفاية الكورتيكوستيرويدات

References

1. If such a taper is not successful, or there is toxicity from the corticosteroids, one should consider the addition of a steroid-sparing agent, such as methotrexate or azathioprine.
2. When an inadequate response to corticosteroids is noted, cytotoxic agents are often used.
3. Methotrexate is one of the most commonly used corticosteroid-sparing therapies for sarcoidosis, due to its effectiveness, low cost and, at the dosages used to treat sarcoidosis, relatively low risk of side effects compared to other cytotoxic agents.