علاج داء الليستيريات الغازي مع ضعف المناعة أو التهاب السحايا أو التهاب الشغاف

References

• Most experts recommend adding gentamicin to ampicillin therapy for the treatment of bacteraemia in persons with impaired immunity (including neonates), and all cases of meningitis and endocarditis.
• High dose antimicrobial therapy should be used in all cases of bacteraemia/possible bacteraemia.
• Ampicillin is the preferred agent, although penicillin is likely to be as effective.
• Gentamicin is discontinued once the patient improves.
• Bacteremic patients without CSF abnormalities can be treated for 2 weeks; meningitis should be treated for 3 weeks; relapses have been documented with shorter durations of therapy.
• Longer durations of therapy are needed for encephalitis, brain abscess and endocarditis, and should be considered in any invasive infection in an immunocompromised person.