ما هو علاج الورم الشحمي غير المتمايز المتقدم أو النقيلي؟

References

DOI: 10.1016/j.ctrv.2024.102846

• Anthracycline-based therapy, either as a single agent (doxorubicin or epirubicin) or as part of a combination (doxorubicin or epirubicin in combination with ifosfamide), is considered the front-line standard for metastatic DDLPS.
• While significant progress has been made in the systemic treatment of liposarcoma, standard first-line chemotherapy for DDLPS remains an anthracycline-based regimen, most commonly doxorubicin at a dose of 75 mg/m2/cycle.
• However, response rates are higher with combination treatment, thus the addition of ifosfamide is considered in patients with oligometastatic disease who could go on to potentially curative treatments or for those patients with rapidly progressive and/or symptomatic disease.