الحزاز الصلب التناسلي لدى النساء — الخطوة التالية عندما لا تُحقق الكورتيكوستيرويدات الموضعية الهدأة

References

DOI: 10.1111/jdv.20083

• We recommend ultrapotent or potent topical corticosteroids in women with genital lichen sclerosus.
• We suggest topical calcineurin inhibitors in women with genital lichen sclerosus as second choice or as an additional treatment if topical corticosteroids are contraindicated or insufficient. (off label)
• We suggest intralesional corticosteroids to hyperkeratotic lesions in women with topical steroid-resistant genital lichen sclerosus (provided malignancy has been excluded).
• In conclusion, TCIs twice daily for at least 12 weeks have some effect in suppressing symptoms (pruritus, burning, dyspareunia) in LS; however, clinical signs are usually better treated by potent topical steroids.