علاج داء هستيوسيتوز خلايا لانغرهانس أحادي البؤرة لدى البالغين بدون داء السكري الكاذب

References

DOI: 10.1182/blood.2021014343

• The proposed classification system differentiates between unifocal (solitary lesion) and single-system multifocal disease (>1 lesion).
• For unifocal LCH (except DI), observation or local therapies such as surgical excision, intralesional steroids, or radiation are recommended as first-line treatments.
• Surgical resection may be preferred depending on the disease location but should only be attempted if not heroic or mutilating.
• Depending on the location, intralesional corticosteroid therapy (eg, methylprednisone or triamcinolone) or, especially in the case of an accompanying soft tissue component, radiation therapy (eg, 10-20 Gy) may offer an excellent and durable response.
• Other unifocal LCH FDG-PET/CT or CT/MRI in 2-3 mo.