علاج السكتة الدماغية الإقفارية الحادة مع العجز العصبي المعيق لدى البالغين المراجعين خلال 4.5 ساعة

References

DOI: 10.1161/STR.0000000000000513

1. In adult patients with AIS presenting within 4.5 hours of symptom onset or last known well and eligible for IVT, tenecteplase at a dose of 0.25 mg/kg body weight (max 25 mg) or alteplase at a dose of 0.9 mg/kg body weight is recommended to improve functional outcomes.
2. In adult patients with AIS with disabling deficits, regardless of NIHSS score, and eligible for IVT, faster treatment improves functional outcomes.
3. Patients with AIS who have elevated BP and are otherwise eligible for treatment with IVT should have their SBP lowered to <185 mm Hg and diastolic blood pressure (DBP) <110 mm Hg before IVT therapy is initiated to reduce hemorrhagic complications.
4. BP should be maintained at <180/105 mm Hg for at least the first 24 hours after IVT treatment.