علاج التهاب القولون الإقفاري: الإدارة الداعمة في الخط الأول

References

DOI: 10.1136/flgastro-2019-101204

• In addition to intravenous fluid resuscitation and blood glucose control (in patients with diabetes), this generally consists of bowel rest and intravenous antibiotics.
• Bowel rest is achieved through fasting, and in the presence of ileus a nasogastric tube placement.
• Consensus suggests combining anaerobic cover with a third-generation cephalosporin or fluoroquinolone.
• There is also a paucity of data regarding duration of antibiotic treatment, but expert consensus has suggested a pragmatic approach that involves review after 72 hours.
• Where clinical improvement is seen, completion of a 7-day course has been advocated.
• Prophylactic low molecular weight heparin is generally recommended, but there is no established role for formal anticoagulation in the acute setting.
• The duration of bowel rest will depend on severity and clinical response, but in general most improve within 2–3 days (although it is thought to take 1–2 weeks for the colon to heal).