التشنجات الرمعية الرضيعية العرضية عند فشل علاج الخط الأول في تحقيق التوقف الكامل للتشنجات وحل الهيبساريثميا

References

• defines symptomatic infantile spasms as those patients with either abnormal development and/or a clear etiology for the infantile spasms and cryptogenic spasms as those occurring in the context of normal development without a clear etiology.
• It is recommended to try two first-line therapies before moving on to other options, as there is less data to support the second-line treatments.
• Studies have reported patients that respond to ACTH after failing corticosteroids and vice-versa.
• The goals of therapy should include a complete cessation of the clinical events and resolution of hypsarrhythmia or modified hypsarrhythmia on video EEG.
• Response is typically seen within 14 days or sooner.

DOI: 10.3978/j.issn.2224-4336.2015.09.01