التشنجات الرضيعية في التصلب الحدبي عندما لم يوقف العلاج الهرموني التشنجات

References

DOI: 10.3978/j.issn.2224-4336.2015.09.01

• For example, patients with tuberous sclerosis are more likely to respond to treatment with vigabatrin, whereas patients without an identified etiology may respond better to hormonal therapy.
• Vigabatrin is the preferred first-line therapy for patients with infantile spasms and tuberous sclerosis, with some studies showing efficacy of greater than 90% in patients with tuberous sclerosis.
• Many other treatment options continue to be explored, including the ketogenic diet, traditional anti-epileptic medications, and resective surgery in select cases.
• Diet ratio ranged from 3 : 1 to 4 : 1.
• The goal of treatment of infantile spasms remains complete cessation of spasms.
• Spasm freedom has been reported in 14-65% of patients within 1-3 months.