عندما لا يتحكم العلاج الهرموني في التشنجات الرضيعية مجهولة السبب

DOI: 10.3978/j.issn.2224-4336.2015.09.01

• defines symptomatic infantile spasms as those patients with either abnormal development and/or a clear etiology for the infantile spasms and cryptogenic spasms as those occurring in the context of normal development without a clear etiology.
• For example, patients with tuberous sclerosis are more likely to respond to treatment with vigabatrin, whereas patients without an identified etiology may respond better to hormonal therapy.
• Many other treatment options continue to be explored, including the ketogenic diet, traditional anti-epileptic medications, and resective surgery in select cases.
• The goal of treatment of infantile spasms remains complete cessation of spasms.
• Spasm freedom has been reported in 14–65% of patients within 1–3 months.