ساركوما كابوسي الإيتروجينية: علاج الخط التالي عندما لا يُسيطر العلاج الموضعي على الآفات

DOI: 10.1111/ddg.14788

• Systemic chemotherapy should be considered in patients with visceral involvement, extensive lymph node involvement, or progressive mucocutaneous involvement.
• Doxorubicine (pegylated, liposomal) is most commonly used.
• Pegylated liposomal doxorubicine at a dose of 20 mg/m² body surface area i.v. every 2–3 weeks can achieve partial remissions in up to 60–80 % of treated patients.
• In most cases, a profound partial remission is achieved after about 3–6 infusions, whereas some patients require more infusions to achieve a response.