علاج قصور الغدة النخامية لدى المرأة الحامل

However, with appropriate hormonal replacement, women with hypopituitarism can expect an uneventful pregnancy and a healthy infant.

We suggest using HC as the preferred GC in pregnancy and increasing the dose based on the individual clinical course; higher doses may be required, in particular during the third trimester.

We recommend HC stress dosing during the active phase of labor, similar to that used in major surgical stress.

During labor and delivery, clinicians should administer a stress dose of GC (50 mg iv HC in the second stage of labor).

For cesarean section, we recommend a dose of 100 mg every 6–8 hours.

We recommend that clinicians monitor fT4 or total T4 levels every 4–6 weeks for women with CH who become pregnant and that these women may require increased L-T4 doses to maintain levels within target ranges for pregnancy.

In pregnant women with pre-existing DI, we suggest continuing DDAVP during pregnancy and adjusting doses if required.