السكتة النخامية حالة طارئة حادة تهدد الحياة يمكن أن تؤدي إلى قصور مفاجئ في الغدة النخامية، وتستلزم التعرف السريري الفوري والإدارة العاجلة.
DOI: 10.1210/jc.2016-2118
Pituitary apoplexy is a life-threatening acute pituitary infarction, hemorrhage, and/or necrosis presenting as rapid onset headache and may include vomiting, fever, meningismus, vision abnormalities, and changes in mental status.
Because acute AI is a major cause of mortality, we recommend GC therapy until a laboratory diagnosis is established and the patient maintains normal pituitary function.
When patients cannot tolerate oral medications, they should begin with a 100–200 mg iv HC bolus followed by 2–4 mg/h by continuous infusion or 50–100 mg injections every 6 hours.
Clinicians should quickly taper HC as indicated and initiate standard oral maintenance doses.
Clinicians have also used high doses of dexamethasone to treat pituitary apoplexy.
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