علاج متلازمة فرط اللزوجة مع الرعاف الثنائي والنزيف المخاطي عند فشل تبادل البلازما

References

• The classic triad of hyperviscosity includes mucosal bleeding, visual abnormalities, and neurological abnormalities.
• For patients with hemorrhagic or central nervous system manifestations, plasma exchange is the therapy of choice and is relatively safe.
• The evidence suggests that bortezomib-based triplet regimens result in the fastest decline in protein levels and should be considered essential when hyperviscosity is seen in multiple myeloma.

DOI: 10.1182/blood-2018-06-846816