علاج مرض هيرشسبرونغ مع التهاب القولون الحاد وانتفاخ البطن

References

• Patients with explosive diarrhea and decreased peripheral perfusion, lethargy, and/or dilated loops of bowel on abdominal radiographs have severe HAEC and should be admitted.
• Intersphincteric botulinum toxin injections are recommended for patients with recurrent or persistent symptoms of outlet obstruction and/or HAEC.
• Injections may need to be repeated 3–6 monthly.
• Botox should be injected under a short general anaesthesia.
• Injections are given in the four quadrants at the level of the dentate line into the anal sphincter musculature.

DOI: 10.1186/s13023-020-01362-3