علاج توسع الأوعية النزفي الوراثي مع فقر الدم بسبب نقص الحديد

References

DOI: 10.1182/blood.2020008739

• The expert panel recommends iron replacement for treatment of iron deficiency and anemia as follows:
• Iron deficiency anemia in HHT results in typical signs and symptoms, including fatigue, reduced exercise tolerance, pica, restless leg syndrome, hair loss, and others, and may considerably worsen symptoms of high-output cardiac failure in patients with significant liver AVMs.
• The expert panel recommends RBC transfusions in the following settings: Hemodynamic instability/shock; Comorbidities that require a higher hemoglobin target; Need to increase the hemoglobin acutely, such as prior to surgery or during pregnancy; Inability to maintain an adequate hemoglobin despite frequent iron infusions.