علاج نقص مثبط C1 الوراثي في الأطفال دون سن 12 عامًا

References

DOI: 10.1111/all.15214

• We recommend C1 inhibitor or icatibant be used for the treatment of attacks in children under the age of 12.
• C1-INH and icatibant are the only approved on-demand treatments for children with HAE-1/2.
• For abdominal attacks, parenteral fluid replacement may be required as children are more susceptible to hypovolemia and dehydration, and extravasation into the peritoneal cavity and the intestinal lumen can be substantial.