علاج اعتلال الدماغ الكبدي عندما تكون الاختبارات العصبية النفسية غير طبيعية لكن العلامات السريرية غائبة أو طفيفة

References

DOI: 10.1016/j.jhep.2022.06.001

• In terms of its severity, HE is qualified as covert (minor or no signs/symptoms but abnormalities on neuropsychological and/or neurophysiological tests) or overt (grades II or over according to the West Haven criteria).
• Patients with covert HE should be treated with non-absorbable disaccharides (LoE 3, strong recommendation, 92% consensus).
• In patients with covert HE, anti-HE treatment should be considered for the purposes of differential diagnosis and to prevent overt HE (LoE 5, strong recommendation, 89% consensus).
• On the other hand, in a situation where covert HE is suspected, even if not confirmed, treatment with non-absorbable disaccharides (and/or rifaximin) could be initiated and, if beneficial, also used as confirmation of the diagnosis (ex juvantibus).