الصداع النصفي المستمر: ماذا تفعل عندما لا يُتحمَّل الإندوميتاسين أو لم يُجدِ نفعاً

DOI: 10.1186/s10194-017-0777-3

For the acute treatment of HC, piroxicam and celecoxib have shown good results, whilst for the prolonged treatment celecoxib, topiramate and gabapentin are good options besides indomethacin.

Gabapentin, topiramate, melatonin and OnabotA seems to be comparable in terms of effectiveness even if, considering the p-values of these comparisons (p = 0.063), a better action for gabapentin and topiramate than melatonin should be hypothesed.

Every patient was classified as a responder if he/she was accredited with, at least, a partial relief. Moreover, as to grade the different therapies better, pain-free patients were sub-classified as complete responders.