التهاب المستقيم السيلاني عند فشل علاج السيفترياكسون

References

• Some infections with MDR N. gonorrhoeae have been successfully treated with ertapenem when ceftriaxone has failed; three days of IV ertapenem 1 g was used for these cases, although this was a pragmatic choice and not guided by clinical trial data.
• In a recent RCT, a single 1 g dose of ertapenem IM was noninferior to ceftriaxone 500 mg IM, although all strains were susceptible to ceftriaxone and had low ertapenem MICs.
• Treatment options are limited and should be guided by the results of antimicrobial susceptibility testing where possible, and in conjunction with expert advice.