داء تخزين الغليكوجين النوع الخامس مع انحلال الربيدات الشديد: ماذا تفعل عندما لم يؤدِّ العلاج بالسوائل إلى تخليص الجسم من البيلة الميوغلوبينية أو استعادة وظيفة الكلى

References

DOI: 10.1016/j.nmd.2021.10.006

• Patients with severe rhabdomyolysis should be treated with adequate fluid administration to prevent renal impairment or be put on dialysis if warranted.
• Myoglobinuria due to rhabdomyolysis can produce ARF, but data from large cohorts of patients suggest that this emergency complication is a rare event in both GSD V and GSD VII.
• Standard criteria for dialysis initiation are: fluid overload unresponsive to loop diuretics, and electrolyte disturbances such as hyperkalaemia, metabolic acidosis and uraemic encephalopathy.