علاج داء تخزين الغليكوجين النوع الأول مع فرط الترشيح المستمر والبيلة البروتينية

DOI: 10.1038/gim.2014.128

• Consider initiating an ACE inhibitor or ARB with evidence of hyperfiltration (sustained estimated GFR >140 ml/min/1.73 m²).
• Initiate an ACE inhibitor or ARB for persistent microalbuminuria (>30 μg albumin/mg creatinine).
• Initiate an ACE inhibitor or ARB for frank proteinuria (>0.2 mg protein/mg creatinine).
• Use of either an angiotensin-converting enzyme (ACE) inhibitor or an angiotensin receptor blocker (ARB) medication by itself can be efficacious.
• There are also data showing that GSD I patients treated with angiotensin blockade show improvement in their degree of glomerular hyperfiltration and can demonstrate restored normal rates of GFR for some time.