علاج ورم الخلايا العملاقة في عظام الأطراف في المرحلة 1 أو 2 من نظام كامباناتشي

References

DOI: 10.3390/curroncol31040157

• For Campanacci stages 1 and 2, curettage is recommended to preserve the joints and to achieve good postoperative function.
• The recommendation indicates aggressive curettage with a sharp curet and a high-speed burr.
• The use of adjuvants (e.g., phenol, ethanol, argon beam coagulator, microwave, cautery, and liquid nitrogen) is also recommended.
• Therefore, the use of 0.05% chlorhexidine gluconate solution for washing after the curettage of GCTB may serve as a chemical adjuvant.
• Cement, hydroxyapatite, β-tricalcium phosphate, and allograft are the materials of choice for filling bone defects.
• Filling the subchondral bone with allograft tip bone, followed by the use of cement, is recommended.
• For such patients who undergo filling with cement and do not receive bone grafting, additional plate fixation is an option.
• In the distal femur, bone chips and plate fixation can be used to reduce damage to the subchondral bone and prevent pathological fracture, respectively.
• Based on the above reports, it is not recommended to administer preoperative denosumab before the curettage of GCTB in the extremities of patients in whom joint preservation may be achieved.