ما هو علاج التهاب الشرايين ذو الخلايا العملاقة؟ إدارة الخط الأول

References

DOI: 10.1136/ard-2022-223429

• Glucocorticoids (GC) are the standard treatment for GCA and PMR.
• GCA is a medical emergency because of the imminent risk of sight loss and other ischaemic events and, therefore, requires immediate treatment; management usually requires multidisciplinary collaboration.
• The treatment target of GCA and PMR should be remission; remission is the absence of clinical symptoms and systemic inflammation.
• They most commonly include the absence of clinical symptoms related to GCA and/or PMR and the normalisation of acute phase reactants, particularly ESR and CRP.
• Disease activity in GCA and PMR should be monitored regularly, as frequently as every 1–4 weeks until remission has been achieved, and at longer monitoring intervals (eg, between 3 and 6 months) in patients in stable remission on therapy; monitoring of patients off therapy should be discussed on an individual basis.