خلل التوعية الهضمي: الإدارة عند عدم السيطرة على النزيف بالعلاج الدوائي

References

DOI: 10.1002/14651858.CD014582.

• Endoscopic management choices include Argon plasma coagulation, bipolar electrocoagulation, endoscopic resection, monopolar electrocoagulation, heater probe coagulation, laser photocoagulation, mechanical hemostasis, neodymium doped yttrium aluminum garnet, sclerotherapy, and cryotherapy.
• Novel endoscopic options for the management of angiodysplasia are continuously being developed, including techniques such as radiofrequency ablation, and the application of newer topical hemostatic agents, e.g. TC-325.
• Given that a significant portion of people with GI angiodysplasia are elderly, and often have comorbidities, it is advisable to approach endoscopic interventions cautiously, typically reserving them as a second-line therapy.
• Nevertheless, management is mainly assessed based on the cessation of bleeding, prevention of rebleeding, and improvement in a person's clinical status.
• Stability of hemoglobin/hematocrit levels: no further drop beyond 1 g/dL for hemoglobin and 5% for hematocrit following the intervention