علاج خلل التعظم الليفي للعظام مع ألم العظام المستمر في نقص فوسفات الدم بوساطة FGF-23

References

1. The first step in the pharmacological management of FD is to ensure supplementation (not correction) of hypophosphatemia if present (see above), and vitamin D repletion (according to national guidelines).
2. Importantly, hypophosphatemia should be corrected as best a possible for least 6 months prior to initiating bisphosphonates.
3. The dose of phosphate supplement should be titrated to maintain serum phosphate at the lower end or just below the normal laboratory reference range for serum phosphate.
4. The aim of initial dosing is to establish whether bisphosphonates are effective in providing pain relief.