ألم العظام في الخلل التليفي العظمي عندما لا يُحسّن التحويل إلى البيسفوسفونات الوريدي درجات الألم

References

DOI: 10.1186/s13023-019-1102-9

• Bone therapies should be tried before recommending tramadol and other opioids.
• For analgesics, consider paracetamol/acetaminophen as first line, followed by NSAIDs, if benefits outweigh cardiovascular, renal and gastro-intestinal risk.
• If neuropathic features such as burning or stabbing pain are present, consider an atypical analgesic ladder, e.g. amitriptyline, gabapentin, pregabalin and duloxetine.
• The strategy is to induce symptom remission.