علاج الفيبروميالجيا في حالات الألم الشديد

References

DOI: 10.1136/annrheumdis-2016-209724

• Pharmacological therapies (all 'weak for') should be considered for those with severe pain (duloxetine, pregabalin, tramadol) or sleep disturbance (amitriptyline, cyclobenzaprine, pregabalin).
• A recent Cochrane review reported patients receiving active treatment were more likely to have 30% pain reduction, RR 1.37, 95% CI 1.22 to 1.53, with a 'number needed to benefit' (NNTB) over placebo of 9, 95% CI 7 to 13.
• Those in the active arm were more likely to have 30% improvement in pain (RR 1.77, 95% CI 1.26 to 2.48).