علاج سرطان قناة فالوب المتقدم (المرحلة FIGO III أو IV) في المريضات ذوات الاحتمالية العالية للاستئصال الجراحي الأمثل للورم

References

DOI: 10.1200/JOP.18.00662

National Comprehensive Cancer Network recommends that any woman with suspected epithelial ovarian cancer be evaluated by a gynecologic oncologist, because optimal surgical debulking by a skilled physician is central to the initial management of patients with advanced, stage III or IV disease.

ASCO states that although primary cytoreductive surgery is preferred for patients with a high likelihood of achieving optimal debulking, women with high perioperative risk or a low likelihood of achieving optimal cytoreduction should receive neoadjuvant chemotherapy followed by possible interval surgery.

For those patients who do undergo upfront cytoreductive surgery, adjuvant chemotherapy includes a platinum doublet, traditionally carboplatin and paclitaxel.

Although the goal of cytoreductive surgery is no gross residual, debulking is considered optimal if residual disease is 1 cm or less in maximum diameter or thickness.