ساركوما إيوينغ مع توضّع الورم الأولي في الحوض غير العجزي: الإدارة السريرية

References

DOI: 10.1016/j.annonc.2021.08.1995

• The interval-compressed VDC/IE regimen showed superiority to VIDE for both event-free survival and OS, with similar toxicity, and it is currently the preferred first-line treatment in ES [I, B].
• Generally, up to nine cycles of induction ChT is delivered after biopsy, followed by local therapy, and consolidation thereafter.
• Overall treatment duration is 10-12 months.
• Complete surgical excision, where feasible, is regarded as the best modality of local control, given the higher risk of LR when RT is used as the sole treatment [IV, A].
• Also, adjuvant RT should be considered in patients with non-sacral pelvic ES regardless of surgical margins, tumour volume or histological response, as this was shown to have superior local control and survival outcomes compared with surgery alone [II, B].