ارتفاع ضغط الدم الأساسي: عندما لا يحقق تعديل نمط الحياة أهداف ضغط الدم

References

DOI: 10.1161/CIR.0000000000001356

• For adults initiating antihypertensive drug therapy, thiazide-type diuretics, long-acting dihydropyridine CCB, and ACEi or ARB are recommended as first-line therapy to prevent CVD.
• In adults with stage 2 hypertension (SBP ≥140 mm Hg and DBP ≥90 mm Hg), initiation of antihypertensive drug therapy with 2 first-line agents of different classes, ideally in a single-pill combination (SPC), is recommended to improve BP control and adherence.
• In adults with stage 1 hypertension (SBP 130–139 mm Hg and DBP 80–89 mm Hg), initiation of antihypertensive drug therapy with a single first-line antihypertensive drug is reasonable, with dosage titration and sequential addition of other agents as needed to achieve BP control.
• In adults with confirmed hypertension who are at increased risk for CVD, an SBP goal of at least <130 mm Hg, with encouragement to achieve SBP <120 mm Hg, is recommended to reduce the risk of cardiovascular events and total mortality.
• In adults with confirmed hypertension who are at increased risk for CVD, a DBP target of <80 mm Hg is recommended to reduce the risk of cardiovascular events and total mortality.