علاج سرطان المريء المبكر (cT1 N0 M0) مع خلل التنسج الظهاري عالي الدرجة أو أورام T1

DOI: 10.1016/j.annonc.2022.07.003

Endoscopic en bloc resection, using either endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD), is the treatment of choice for lesions with intraepithelial high-grade dysplasia and most T1 tumours.

For both histological subtypes, patients with involved deep endoscopic resection margins or significant risk factors for lymph node metastases should be offered further resective surgery with appropriate lymphadenectomy; however, chemoradiotherapy (CRT) could be considered as a treatment option for stage IA SCC with organ preservation.