الاعتلال الدماغي الصرعي مع CSWS في سياق آفة دماغية هيكلية أحادية الجانب قابلة للاستئصال

References

DOI: 10.1016/j.jpeds.2021.01.032

• Surgeries have typically included focal resection for cases of unilateral structural brain lesions (malformations or areas of injury) or multiple subpial transections, a procedure that has fallen out of favor as it was shown to be ineffective at resolving CSWS or enhancing cognitive outcomes or quality of life.
• Our data support recommendations made by prior authors that epilepsy surgery evaluation should be considered for children with CSWS caused by unilateral brain lesions amenable to resection.
• The clinical response was defined as clinical improvement in neurocognitive function, seizures, or the EEG after therapy as judged and documented in the medical record by the treating neurologist.
• The SWI response was defined by a 50% reduction in the sleep SWI when comparing the post- and pre-treatment EEGs.