خيارات العلاج الأول لالتهاب المريء اليوزيني

References

DOI: 10.1053/j.gastro.2020.02.038

• In patients with symptomatic esophageal eosinophilia, the AGA/JTF suggests using proton pump inhibition over no treatment.
• In patients with EoE, the AGA/JTF recommends topical glucocorticosteroids over no treatment.
• Eight double-blind placebo-controlled studies enrolling 437 patients followed for a mean of 8 weeks compared treatment with topical budesonide or topical fluticasone to placebo.
• In patients with EoE, the AGA/JTF suggests using elemental diet over no treatment.
• In patients with EoE the AGA/JTF suggests using an empiric six-food elimination diet over no treatment.
• In patients with EoE, the AGA/JTF suggests allergy testing-based elimination diet over no treatment.
• With the exception of the recommendation on esophageal dilation, the guidelines are based on the failure to achieve histologic remission of <15 eosinophils/high power field (eos/hpf) as the definition of treatment effect.
• Until such metrics are established, a threshold of <15 eos/hpf to define an adequate therapeutic response serves as a response criterion until a better measure is established.