تضخم بطانة الرحم غير النمطي لدى النساء الراغبات في الحفاظ على الخصوبة أو اللواتي لا تُعدّ الجراحة خياراً بالنسبة لهن

Women wishing to retain their fertility should be counselled about the risks of underlying malignancy and subsequent progression to endometrial cancer.

Once fertility is no longer required, hysterectomy should be offered in view of the high risk of disease relapse.

If this is not possible or declined, a further cycle of progestogen treatment can be attempted.

In a study of 33 women with relapsed atypical hyperplasia, 85% (28/33) regressed following retreatment with oral medroxyprogesterone given for 6 months.