داء فيروس إيبولا مع الملاريا الشديدة: الغيبوبة والحماض الاستقلابي وفقر الدم الشديد

References

1. Definition of severe malaria – severe malaria usually manifests with one or more of the following: coma (cerebral malaria), metabolic acidosis, severe anaemia, hypoglycaemia, acute renal failure or acute pulmonary oedema.
2. Adults, including pregnant women: 2.4 mg/kg/dose IV initially, followed by 2.4 mg/kg/dose at 12 hours, 24 hours and 48 hours after the initial dose for a total of four doses over a period of 3 days.
3. Infants and children < 20 kg: 3 mg/kg/dose initially, followed by 3 mg/kg/dose at 12 hours, 24 hours and 48 hours after the initial dose for a total of four doses over a period of 3 days.
4. Transition to oral therapy at least 4 hours after the last dose of artesunate.
5. Stop treatment once malaria testing is negative or the treatment course is finished.