علاج السرطانة القنوية في الموضع في الثدي

References

DOI: 10.1093/jjco/hyae122

• The standard local treatment for DCIS is breast-conserving surgery (BCS) or total mastectomy, the same as the treatment options for invasive carcinoma.
• The National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines recommend that patients with DCIS should undergo 'BCS without lymph node surgery' or 'total mastectomy with SLNB'.
• The Society of Surgical Oncology (SSO)—American Society for Radiation Oncology (ASTRO)—American Society of Clinical Oncology (ASCO) Consensus Guideline recommends a negative surgical margin of at least 2 mm based on this meta-analysis showing a reduced risk of ipsilateral breast tumor recurrence (IBTR).
• Achieving negative histological margins is crucial for patients undergoing BCS, as positive surgical margins are one of the important risk factors for local recurrence (LR).