عندما يفشل علاج GLP-1 أو العلاج المزدوج بـ GIP/GLP-1 في تحقيق هدف إنقاص الوزن في السمنة المُحدَثة بالأدوية

References

In people with diabetes not reaching weight treatment goals, modify or intensify treatment with additional approaches, including structured lifestyle management programs, metabolic surgery, and additional or alternative pharmacologic agents.

Should use of these medications not result in achievement of weight management goals, or if they are not tolerated or are contraindicated, other obesity treatment approaches should be considered.

Unless clinical circumstances (such as poor tolerability) or other considerations (such as financial expense or individual preference) suggest otherwise, those who achieve sufficient early weight loss upon starting a chronic obesity pharmacotherapy (typically defined as >5% weight loss after 3 months of use) should continue the medication long-term.