تخثر الأوعية الداخلي المنتشر مع النزيف النشط أو الخطر العالي للنزيف: نهج الإدارة

References

• Transfusion of platelets or plasma (components) in patients with DIC should not primarily be based on laboratory results and should in general be reserved for patients that present with bleeding (Grade C, Level IV).
• In patients with DIC and bleeding or at high risk of bleeding (e.g. postoperative patients or patients due to undergo an invasive procedure) and a platelet count of <50 × 10&sup9;/l, transfusion of platelets should be considered (Grade C, Level IV).
• If transfusion of FFP is not possible in patients with bleeding because of fluid overload, consider using factor concentrates such as prothrombin complex concentrate, recognising that these will only partially correct the defect because they contain only selected factors, whereas in DIC there is a global deficiency of coagulation factors (Grade C, Level IV).
• Severe hypofibrinogenaemia (<1 g/l) that persists despite FFP replacement may be treated with fibrinogen concentrate or cryoprecipitate (Grade C, Level IV).