علاج الذئبة الحمامية القرصية مع الآفات الجلدية الشديدة أو المنتشرة

References

• We recommend antimalarials as first-line and long-term systemic treatment in all CLE patients with severe or widespread skin lesions, in particular in patients with the risk of scarring and development of systemic disease.
• In severe or widespread active CLE lesions, systemic corticosteroids are recommended as first-line treatment in addition to antimalarials.
• We recommend thalidomide for selected refractory CLE patients, preferably in addition to antimalarials.
• We suggest a starting dose of 100 mg per day and, after clinical effectiveness, to taper to a minimum dose.