علاج الذئبة الحمامية القرصية مع آفات جلدية شديدة أو منتشرة، أو خطر التندب والتطور الجهازي

References

1. We recommend antimalarials as first-line and long-term systemic treatment in all CLE patients with severe or widespread skin lesions, in particular in patients with the risk of scarring and development of systemic disease.
2. In severe or widespread active CLE lesions, systemic corticosteroids are recommended as first-line treatment in addition to antimalarials.
3. We recommend topical corticosteroids as first-line treatment for a time limited up to some weeks in all CLE lesions.
4. In patients with widespread disease and/or the risk of scarring, we recommend concomitant treatment with antimalarials.
5. We recommend to taper the dose of systemic corticosteroids to a minimum with the aim to discontinue the administration, as soon as the disease being treated is under control.