علاج الورم النجمي المنتشر (IDH-طافر، 1p19q غير محذوف، الدرجة 2 من تصنيف منظمة الصحة العالمية للجهاز العصبي المركزي) مع عوامل إنذارية مواتية بعد الجراحة — عند تأجيل العلاج الإشعاعي والعلاج الكيميائي

References

DOI: 10.1200/JCO-25-00250

• In astrocytoma, IDH-mutant, 1p19q non-codeleted, CNS WHO grade 2, initial radiation therapy and chemotherapy (with temozolomide or PCV) may be deferred until radiographic or symptomatic progression in some people with favorable prognostic factors (eg, complete resection, younger age) or concerns about short- and long-term toxicity given the natural history of the disease.
• People with astrocytoma, IDH-mutant, 1p19q non-codeleted, CNS WHO grade 2 (low grade diffuse glioma) should be offered radiation therapy with adjuvant chemotherapy (temozolomide or PCV) (Evidence quality: Moderate; Strength of recommendation: Strong)