ما هو علاج داء السكري من النوع 1 الذي يبدأ عند التشخيص؟

References

DOI: 10.1016/j.jcjd.2017.10.012

• People with type 1 diabetes are initiated on insulin therapy immediately at diagnosis.
• In adults with type 1 diabetes, basal-bolus injection therapy or CSII as part of an intensive diabetes management regimen should be used to achieve glycemic targets.
• Basal insulin is given once or twice a day and includes long-acting insulin analogues and intermediate-acting insulin neutral protamine Hagedorn (NPH).
• In adults with type 1 diabetes using basal-bolus injection therapy or CSII, rapid-acting insulin analogues should be used in place of regular insulin to improve A1C and to minimize the risk of hypoglycemia.
• The U-100 long-acting analogues, insulin detemir and insulin glargine (with rapid-acting insulin analogues for meals) resulted in lower fasting plasma glucose (FPG) levels and less hypoglycemia or nocturnal hypoglycemia compared with once- or twice-daily NPH insulin.
• Preprandial injections of rapid-acting insulin analogues result in a lower postprandial glucose and improved overall glycemic control.