علاج مرض الترسب الكثيف مع طفرة مرضية محددة في جين العامل المكمل H (CFH)

In patients with defined pathologic mutations of CFH (and perhaps those carrying CFH risk alleles), specific treatment guidelines should include infusion of fresh frozen plasma or plasmapheresis and exchange with plasma, rather than albumin, to provide functionally intact factor H (recombinant factor H is not currently available).

In the presence of pathologic mutations in CFH that lead to absent or dysfunctional factor H protein, plasma infusion should be considered (with the use of recombinant factor H in the future).