علاج مرض الترسبات الكثيفة: السيطرة المكثفة على ضغط الدم وتقليل البروتينية

References

DOI: 10.1681/ASN.2007030356

• Nonspecific measures that are effective in slowing progression of numerous chronic glomerular diseases include aggressive BP control and reduction of proteinuria.
• Angiotensin-converting enzyme (ACE) inhibitors and angiotensin II type 1 receptor blockers are first-line agents to decrease proteinuria, improve renal hemodynamics, and possibly limit leukocyte infiltration in the kidney.
• Although not widely used in children, in the presence of hyperlipidemia, lipid-lowering agents such as hydroxymethylglutaryl CoA reductase inhibitors may also delay progression of renal disease, correct endothelial cell dysfunction, and alter long-term atherosclerotic risks.